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CD276 Rabbit Polyclonal Antibody

CAT: 0992-ER1803-36Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-36Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
CAS Number
9007-83-4
Product Name Alternative
4Ig B7 H3 antibody 4Ig-B7-H3 antibody AU016588 antibody B7 H3 antibody B7 homolog 3 antibody B7-H3 antibody B7H3 antibody B7RP-2 antibody CD_antigen=CD276 antibody CD276 antibody CD276 antigen antibody CD276 molecule antibody CD276_HUMAN antibody Costimulatory molecule antibody Flags: Precursor antibody PSEC0249 antibody UNQ309/PRO352 antibody
Abbreviation
B7-H3, CD276, B7H3, PSEC0249, UNQ309/PRO352
Swiss Prot
Q5ZPR3 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human CD276 aa 1-466 / 534.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
MCF7 cell lysate, HEK-293 cell lysate, LoVo cell lysate, U-2 OS cell lysate, LNCaP cell lysate, SH-SY5Y cell lysate, THP-1 cell lysate, HCT 116 cell lysate, MCF7.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IF-Cell: 1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 57 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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