UBA3 Mouse Monoclonal Antibody [1B5-2-3]

UBA3 Mouse Monoclonal Antibody [1B5-2-3]

• Description: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Product Name Alternative: DKFZp566J164 antibody EC 6.3.2. antibody hUba3 antibody MGC22384 antibody NEDD8 activating enzyme E1 catalytic subunit antibody NEDD8 activating enzyme E1C antibody Nedd8 activating enzyme hUba3 antibody NEDD8-activating enzyme E1 catalytic subunit antibody NEDD8-activating enzyme E1C antibody uba3 antibody UBA3 ubiquitin activating enzyme E1 homolog antibody UBA3_HUMAN antibody UBE1C antibody Ubiquitin activating enzyme 3 antibody Ubiquitin activating enzyme E1C antibody Ubiquitin-activating enzyme 3 antibody Ubiquitin-activating enzyme E1C antibody Ubiquitin-like modifier-activating enzyme 3 antibody
• Abbreviation: UBA3
• CAS Number: 9007-83-4
• Swiss Prot: Q8TBC4 Human
• Cellular Locus: Cytosol, nucleus, cytoplasm.
• Host: Mouse
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein within Human UBA3 aa 220-424 / 463.
• Isotype: IgG2a
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: 293T cell lysate, HepG2 cell lysate, EA.hy926, F9, SiHa, human lung tissue, human lung carcinoma tissue, human skin tissue, human breast tissue, human esophagus tissue, SiHa cells.
• Concentration: 2 mg/mL
• Dilution: WB:1:500-1:2,000;IF-Cell:1:50-1:100;IHC-P:1:100-1:500;FC:1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 52 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No