Calreticulin Mouse Monoclonal Antibody [7B1]

• Description:

  Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.

• Product Name Alternative:

  Autoantigen RO antibody CALR antibody CALR protein antibody CALR_HUMAN antibody Calregulin antibody Calreticulin antibody cC1qR antibody CRP55 antibody CRT antibody CRTC antibody Endoplasmic reticulum resident protein 60 antibody Epididymis secretory sperm binding protein Li 99n antibody ERp60 antibody FLJ26680 antibody grp60 antibody HACBP antibody HEL S 99n antibody RO antibody Sicca syndrome antigen A (autoantigen Ro; calreticulin) antibody Sicca syndrome antigen A antibody SSA antibody

• Abbreviation:

  ERp60, CALR, CRTC

• Swiss Prot:

  P27797 Human

• Cellular Locus:

  Endoplasmic reticulum. Secreted. Cytosol.

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant full length protein corresponding to Human Calretinin aa 1 to the C-terminus.

• Isotype:

  IgG1

• Conjugation:

  Non-conjugated

• Type:

  Mouse monoclonal Antibody

• Applications:

  WB, IHC-P, IF-Cell, FC

• Positive Control:

  HepG2 cell lysate, HeLa cell lysate, HL-60 cell lysate, HepG2, human prostate cancer tissue, Jurkat.

• Concentration:

  2 mg/mL

• Dilution:

  WB: 1:5,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

• Purity:

  Protein G affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 48 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4