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Methylbiocin

CAT: 0804-HY-162711Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162711Size:1 Each
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Description
Methylbiocin is an ATP competitive inhibitor for human CMG helicase with an IC50 of 59 µM. Methylbiocin exhibits potential in cancer research[1].
CAS Number
23370-12-9
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methylbiocin.html
Smiles
CC1=C(O[C@H]2[C@H](O)[C@H](OC(C3=CC=C(C)N3)=O)[C@@H](OC)C(C)(C)O2)C=CC4=C1OC(C(NC(C5=CC(C/C=C(C)/C)=C(O)C=C5)=O)=C4O)=O
Molecular Formula
C36H40N2O11
Molecular Weight
676.71
References & Citations
[1]Xiang S, et al., Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function. Mol Cancer Ther. 2024 Jul 10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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