GW695634

CAT: 0804-HY-123330Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-123330Size:1 Each

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Description

GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz -resistant and Nevirapine (HY-10570) -resistant HIV and AIDS viruses[1].

CAS Number

457635-65-3

UNSPSC

12352005

Target

HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gw695634.html

Smiles

CCC(NS(=O)(C1=CC=C(C(C)=C1)NC(COC2=CC=C(C=C2C(C3=CC(C#N)=CC(Cl)=C3)=O)Cl)=O)=O)=O

Molecular Formula

C26H21Cl2N3O6S

Molecular Weight

574.43

References & Citations

[1]M de Serres, et al. "The disposition and metabolism of GW695634: a non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS." Xenobiotica 40.6 (2010) : 437-445.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

GW695634

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