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Ligustroside

CAT: 0804-HY-N3383Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3383Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ligustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages[1][2].
CAS Number
35897-92-8
Product Name Alternative
Ligstroside
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ligustroside.html
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1CCOC(C[C@H]2/C([C@@H](OC=C2C(OC)=O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=C\C)=O
Molecular Formula
C25H32O12
Molecular Weight
524.51
References & Citations
[1]Grewal R, et al. Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Exp Neurol. 2020;328:113248. |[2]Liu J, et al. Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus. J Nat Med. 2015;69 (1) :135-141.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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