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CrBKA

CAT: 0804-HY-153104-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-153104-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity[1].
CAS Number
2260810-48-6
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crbka.html
Purity
98.46
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C1=CC=C(NC([C@H](CCCCNC(/C=C/C)=O)NC(OCC2=CC=CC=C2)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C28H31N3O6
Molecular Weight
505.56
References & Citations
[1]Wang H L, et al. Interactions between sirtuins and fluorogenic small-molecule substrates offer insights into inhibitor design. Rsc Advances, 2017, 7 (58) : 36214-36222.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT6

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CatalogName
MBS5817030CrBKA

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