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Isbogrel

CAT: 0804-HY-119890-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119890-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isbogrel (CV-4151) is a potent selective inhibitor of thromboxane A2 synthase. Isbogrel has oral activity and inhibits blood TXA2 generation with an ID50 value of 0.04 mg/kg[1].
CAS Number
89667-40-3
Product Name Alternative
CV-4151
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isbogrel.html
Solubility
10 mM in DMSO
Smiles
OC(CCCC/C=C(C1=CN=CC=C1)\C2=CC=CC=C2)=O
Molecular Formula
C18H19NO2
Molecular Weight
281.35
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Z Terashita, et al. Effects of thromboxane A2 synthase inhibitors (CV-4151 and ozagrel), aspirin, and ticlopidine on the thrombosis caused by endothelial cell injury. Thromb Res. 1995, 77, 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5777339Isbogrel

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