Products for Research Use Only
RegisterLogin

Dihydroergocristine mesylate

CAT: 0607-B6313-10Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0607-B6313-10Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5-HT receptor antagonist and partial agonist of adrenergic and dopaminergic receptors
CAS Number
24730-10-7
Product Name Alternative
(6aS,9S,10aS)-N-((2S,5S,10aS,10bR)-5-benzyl-10b-hydroxy-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide methanesulfonate
Field of Research
GPCR G protein Adrenergic Receptor
Purity
0.98
Form
White solid
Solubility
<17.7mg/ml in DMSO
Smiles
OS(=O)(C)=O.O[C@@]1(N(C2=O)[C@@H](CC3=CC=CC=C3)C(N4[C@H]1CCC4)=O)O[C@]2(C(C)C)NC([C@H]5C[C@@H]6[C@H](CC7=CNC8=CC=CC6=C78)N(C)C5)=O
Molecular Formula
C35H41N5O5·CH3SO3H
Molecular Weight
707.84
Shipping Conditions
Blue ice
Storage Conditions
Store at RT.

Chemical Information

Dihydroergocristine Mesylate

Dihydroergocristine mesylate is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. It is also a component of ergoloid mesylate (codergocrine mesilate), a mixture of ergot alkaloid derivatives that is used as a vasodilator and has shown mild benefits in the treatment of vascular dementia. It has a role as a geroprotector, a vasodilator agent and an alpha-adrenergic antagonist. It contains a dihydroergocristine.

CAS Number24730-10-7
PubChem CID444034
IUPAC Name(6aR,9R,10aR)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;methanesulfonic acid
Molecular FormulaC36H45N5O8S
Molecular Weight707.8
Topological Polar Surface Area181
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count50
Formal Charge0
Complexity1300
SMILES
CC(C)[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@@H]5C[C@H]6[C@@H](CC7=CNC8=CC=CC6=C78)N(C5)C.CS(=O)(=O)O
InChI
InChI=1S/C35H41N5O5.CH4O3S/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34;1-5(2,3)4/h4-7,9-12,18,20,23,25,27-29,36,44H,8,13-17,19H2,1-3H3,(H,37,41);1H3,(H,2,3,4)/t23-,25-,27-,28+,29+,34-,35+;/m1./s1
InChIKey
SPXACGZWWVIDGR-SPZWACKZSA-N
Chemical Structure
2D Structure
2D structure of Dihydroergocristine Mesylate
CAS: 24730-10-7
CID: 444034
Formula: C36H45N5O8S
MW: 707.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight707.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass707.29888458
Monoisotopic Mass707.29888458
Topological Polar Surface Area181 Ų
Heavy Atom Count50
Formal Charge0
Complexity1300
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
B1554-50Benztropine mesylate
B1720-1000Danofloxacin Mesylate
A3791-25Saquinavir mesylate
B1720-5000Danofloxacin Mesylate
A8646-5Trovafloxacin mesylate
B6327-50Dihydroergotoxine mesylate
B6419-50Tetrindole mesylate
B6419-10Tetrindole mesylate
B2003-100Pefloxacin Mesylate
B2124-10Reboxetine mesylate

Alternative Products

CatalogName
BUP12047-01Dihydroergocristine mesylate
HY-N2319-01Dihydroergocristine (mesylate)
BML-NS108-1000Dihydroergocristine . mesylate
HY-N2319RDihydroergocristine (mesylate) (Standard)
AR-D05786-01Dihydroergocristine Mesylate EP Impurity F
RM-D093100-01Dihydroergocristine Mesilate
TRC-B288465-1MGDihydroergocristine N-Oxide
AR-E01673-01Dihydroergocristine EP Impurity A
AR-E01672-01Dihydroergocristine Impurity L
AR-E01671-01Dihydroergocristine Impurity C

Popular Products