Rolapitant HCl

• Description:

  Orally active neurokinin NK1 receptor antagonist.

• Product Name Alternative:

  (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]dec-1-en-2-ol hydrochloride

• Field of Research:

  GPCR G protein NK Receptor

• Purity:

  0.9913

• Solubility:

  insoluble in H2O; ≥28.7 mg/mL in EtOH with ultrasonic; ≥32.9 mg/mL in DMSO

• Smiles:

  C[C@]([H])(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@]2(CC[C@]3(CCC(O)=N3)CN2)C4=CC=CC=C4.Cl

• Molecular Formula:

  C25H27ClF6N2O2

• Molecular Weight:

  536.94

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  552292-08-7 (free base)