TP-020
CAT:
804-HY-101857-01
Size:
1 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TP-020
- CAS Number: 1800025-30-2
- UNSPSC Description: TP-020 (MGAT2-IN-1) is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively.
- Target Antigen: Acyltransferase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/tp-020.html
- Purity: 98.96
- Solubility: DMSO : ≥ 125 mg/mL
- Smiles: O=S(C1=CC2=C(N(C3=NC=C(C4=CC(C(F)(F)F)=NN4C)C=N3)CC2)C(N5C(CCC5)=O)=C1)(NC6=C(F)C=C(Cl)C=C6F)=O
- Molecular Weight: 654.01
- References & Citations: [1]Take K, et al. Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization. PLoS One. 2016 Mar 3;11(3):e0150976.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported