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Razobazam

CAT: 0804-HY-129245Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129245Size:1 Each
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Description
Razobazam (Hoe 175) is a benzodiazepine derivative with cognitive activity. Razobazam has been shown to improve learning performance in socially deprived rats. Razobazam increased avoidance scores by 18% after training. Razobazam caused significant changes in the optical density of certain areas of the rat brain, including a 22% decrease in the lateral habenula and a 25% increase in the ventral tegmental area. Razobazam also caused a 13% increase in optical density in the prefrontal cortex of rats[1].
CAS Number
78466-98-5
Product Name Alternative
Hoe 175
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/razobazam.html
Smiles
O=C1N(C2=C(N(C)C(C1)=O)NN=C2C)C3=CC=CC=C3
Molecular Formula
C14H14N4O2
Molecular Weight
270.29
References & Citations
[1]Functional activity in the brain of socially deprivated rats produced by an active avoidance test after razobazam (Hoe 175) treatment: a 2-deoxyglucose study
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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