Urolithin C
CAT:
804-HY-135897-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Urolithin C
- CAS Number: 165393-06-6
- UNSPSC Description: Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation[1][2].
- Target Antigen: Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species
- Type: Natural Products
- Related Pathways: Apoptosis;Immunology/Inflammation;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;NF-κB
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/urolithin-c.html
- Smiles: O=C1C2=CC(O)=C(O)C=C2C3=CC=C(O)C=C3O1
- Molecular Weight: 244.20
- References & Citations: [1]Slimane Toubal, et al. Urolithin C Increases Glucose-Induced ERK Activation Which Contributes to Insulin Secretion. Fundam Clin Pharmacol. 2020 Feb 21.|[2] Peipei Yin, et al. Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway. RSC Advances. Issue 28, 2017.|[3]Morgane Bayle, et al. Development and Validation of a Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry Method for the Determination of Urolithin C in Rat Plasma and Its Application to a Pharmacokinetic Study. J Pharm Biomed Anal. 2016 Nov 30;131:33-39.
- Shipping Conditions: Room Temperature