Human SLITRK6 Protein, Mouse IgG2a Fc Tag (MALS verified)

Human SLITRK6 Protein, Mouse IgG2a Fc Tag (MALS verified)

• Background: SLIT and NTRK-like protein 6 (SLITRK6) belongs to the SLITRK family. SLITRK6 contains 11 LRR (leucine-rich) repeats, two LRRCT domains and two LRRNT domains. In adult brain, SLITRK6 is highly expressed in putamen and also is expressed in adult, fetal lung and fetal liver. SLITRK6 is also expressed at high levels in some brain tumors. Overexpression of SLITRK6 inhibites neurite outgrowth in cultured neurons.
• Description: Human SLITRK6, Mouse IgG2a Fc Tag (SL6-H5255) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Ser 608 (Accession # Q9H5Y7-1).
• Specifications: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 91.7 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Ser 27 - Ser 608
• Host: HEK 293
• Target: SLITRK6
• Conjugation: Unconjugated
• Tag: C-mFc(mIgG2a)
• Source: Human
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 0.1 EU per μg
• Purity: 95%
• Bioactivity: Immobilized Human SLITRK6, Mouse IgG2a Fc Tag (Cat. No. SL6-H5255) at 2 μg/mL (100 μL/well) can bind Sirtratumab with a linear range of 0.06-31 ng/mL (QC tested).
• Format: Powder
• Buffer: PBS, pH 7.4
• Additives: Trehalose
• Molecular Weight: 91.7 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C