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Neutral protease I

CAT: 0804-HY-131577ASize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131577ASize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin[1].
CAS Number
42613-33-2
Product Name Alternative
Dispase I
UNSPSC
12352204
Target
Collagen
Type
Enzyme
Related Pathways
Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/neutral-protease-i.html
Smiles
[NeutralproteaseI]
References & Citations
[1]K S Stenn, et al. Dispase, a neutral protease from Bacillus polymyxa, is a powerful fibronectinase and type IV collagenase. J Invest Dermatol. 1989 Aug;93 (2) :287-90.
Shipping Conditions
Room Temperature
Storage Conditions
Store at 4°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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