HEK293/FcRn (FCGRT & B2M), GFP Tag Stable Cell Line

• Background:

  FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

• Description:

  FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

• Host:

  HEK293

• Origin Species:

  Human

• Target:

  FcRn (FCGRT & B2M)

• Tag:

  C-GFP | Native

• Applications:

  • Useful for cell-based FcRn (FCGRT & B2M) binding assay.

• Format:

  Liquid

• Shipping Conditions:

  Dry ice

• Storage Conditions:

  Frozen in liquid nitrogen

• Package Size:

  1Vial*2

• Species:

  Human