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Canniprene

CAT: 0804-HY-N3535-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3535-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM) . Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins[1].
CAS Number
70677-47-3
UNSPSC
12352005
Target
Lipoxygenase; Prostaglandin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/canniprene.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
OC1=C(OC)C=CC(CCC2=CC(OC)=CC(O)=C2)=C1C/C=C(C)\C
Molecular Formula
C21H26O4
Molecular Weight
342.43
References & Citations
[1]Allegrone G, et al. The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some Cannabis sativa Strains. J Nat Prod. 2017 Mar 24;80 (3) :731-734.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
5-LOX

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CatalogName
379770Canniprene

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