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QBS10072S

CAT: 0804-HY-164401Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164401Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
QBS10072S is a bifunctional chemotherapeutic agent, through combination of a cytotoxin and a selective LAT1 transporter substrate. QBS10072S exhibits cytotoxicity in MDA-MB-231 cell and antitumor efficacy in mice. QBS10072S is blood-brain barrier (BBB) penetrable[1].
CAS Number
1802735-28-9
UNSPSC
12352211
Target
EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/qbs10072s.html
Smiles
CC1=C(C[C@@H](CC(O)=O)N)C=C(N(CCCl)CCCl)C=C1
Molecular Formula
C15H22Cl2N2O2
Molecular Weight
333.25
References & Citations
[1]Deng J, et al., A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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