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Thiosemicarbazide

CAT: 0804-HY-Y0032-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0032-01Size:5 g
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Description
Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co (II) and Cu (I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals[1][2][3][1][2][3].
CAS Number
79-19-6
UNSPSC
12352211
Hazard Statement
H300, H412
Target
Orthopoxvirus
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Cancer; Infection; Others
Assay Protocol
https://www.medchemexpress.com/thiosemicarbazide.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
NNC(N)=S
Molecular Formula
CH5N3S
Molecular Weight
91.14
Precautions
H300, H412
References & Citations
[1]Yamashita J. Susceptibility to thiosemicarbazide (an antagonist of vitamin B6), and phylogenetic and ontogenetic development of brain. J Nutr Sci Vitaminol (Tokyo) . 1974;20 (2) :113-9.|[2]Hamrani O, et al. Reaction of thiosemicarbazide with some divalent ions: Synthesis, characterization, molecular modeling, and evaluation of the catalytic and biological activity of the complexes[J]. Inorganic and Nano-Metal Chemistry, 2017, 47 (7) : 1070-1079.|[3]Kozyra P, et al. Potential Anticancer Agents against Melanoma Cells Based on an As-Synthesized Thiosemicarbazide Derivative. Biomolecules. 2022 Jan 18;12 (2) :151.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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