(-) -Integerrimine

• Description :

  (-) -Integerrimine, a pyrrolizidine alkaloid, has antiulcerogenic activity. (-) -Integerrimine is also a mutagenic and weakly clastogenic agent in Drosophila[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H300+H310+H330

• Target :

  Others

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/minus-integerrimine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1O[C@@]2([H])[C@]3([H])N(CC=C3COC([C@](O)([C@@H](C/C1=C\C)C)C)=O)CC2

• Molecular Formula :

  C18H25NO5

• Molecular Weight :

  335.39

• Precautions :

  P260-P262-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

• References & Citations :

  [1]V R Campesato, et al. Recombinagenic activity of integerrimine, a pyrrolizidine alkaloid from Senecio brasiliensis, in somatic cells of Drosophila melanogaster. Environ Mol Mutagen. 1997;29 (1) :91-7.|[2]Walber Toma, et al. Modulation of gastrin and epidermal growth factor by pyrrolizidine alkaloids obtained from Senecio brasiliensis in acute and chronic induced gastric ulcers. Can J Physiol Pharmacol. 2004 May;82 (5) :319-25.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [480-79-5]