6-Mercaptopurine (Standard)

6-Mercaptopurine (Standard)

• CAS Number: 50-44-2
• UNSPSC Description: 6-Mercaptopurine (Standard) is the analytical standard of 6-Mercaptopurine. This product is intended for research and analytical applications. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.
• Target Antigen: Autophagy; Endogenous Metabolite; Nucleoside Antimetabolite/Analog
• Type: Reference Standards
• Related Pathways: Autophagy;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/6-mercaptopurine-standard.html
• Smiles: S=C1NC=NC2=C1NC=N2
• Molecular Weight: 152.18
• References & Citations: [1]Sahasranaman S, et al. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol. 2008 Aug;64(8):753-67.|[2]Liu Q, et al. 6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3. Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1081-92.|[3]Kanemitsu H, et al. 6-Mercaptopurine (6-MP) induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain. Neurotoxicol Teratol. 2009 Mar-Apr;31(2):104-9.
• Shipping Conditions: Room temperature