(R,S,S,R,S)-Boc-Dap-NE

(R,S,S,R,S)-Boc-Dap-NE

• CAS Number: 2994330-72-0
• UNSPSC Description: (R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/r-s-s-r-s-boc-dap-ne.html
• Purity: 98.32
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N1[C@H](CCC1)[C@@H](OC)[C@H](C)C(N[C@@H](C)[C@H](O)C2=CC=CC=C2)=O)OC(C)(C)C
• Molecular Weight: 420.54
• References & Citations: [1]Vaarhorst AA, et al. A metabolomic profile is associated with the risk of incident coronary heart disease. Am Heart J. 2014 Jul;168(1):45-52.e7.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, stored under nitrogen)
• Clinical Information: No Development Reported