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WAY-100289

CAT: 0804-HY-19136Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19136Size:1 Each
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Description
WAY-100289 is an orally active antagonist for 5-HT3 receptor, that exhibits high affinity to the isolated rat vagus nerves with pA2 of 8.9. WAY-100289 inhibits the Bezold-Jarisch reflex in anesthetized and awake rats[1].
CAS Number
136013-69-9
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/way-100289.html
Smiles
O=C(NC(N[C@@H]1C[C@@H](N2C)CC[C@@H]2C1)=O)C3=CC=CC=C3OCC4CC4
Molecular Formula
C20H27N3O3
Molecular Weight
357.45
References & Citations
[1]Rhodes K F, et al. WAY 100289: Pharmacological profile of a novel 5‐HT3 receptor antagonist[J]. Drug development research, 1993, 28 (2) : 128-140.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Lactoferrin

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