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LY550410

CAT: 0804-HY-W684904Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W684904Size:1 Each
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Description
LY550410 is a small-molecule ATP-competitive inhibitor against type I TGF-β receptor kinase, which contains heteroaryl rings for potent binding to the kinase-domain active site. LY550410 modulates TGF-β signalling, thereby regulates gene expression and ultimately cell growth. LY550410 is promising for research of cancers[1].
CAS Number
737791-20-7
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ly550410.html
Smiles
C12=C(C3=C4N(CCC4)N=C3C5=CC=CC=N5)C=CN=C1C=CC=C2
Molecular Formula
C20H16N4
Molecular Weight
312.37
References & Citations
[1]Yingling JM, et al. Development of TGF-beta signalling inhibitors for cancer therapy. Nat Rev Drug Discov. 2004 Dec;3 (12) :1011-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
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