2A3

• Description :

  2A3 is a highly efficient and precise SHAPE reagent with powerful biomembrane penetration capabilities, suitable for both in vivo and in vitro RNA structure detection. 2A3 can not only effectively probe most RNA loops but also better capture local nucleotide dynamics, thus enabling it to readily detect regions of ribonucleoprotein complexes that are typically inaccessible to other compounds[1].

• CAS Number :

  [2765091-45-8]

• UNSPSC :

  12352005

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/2a3.html

• Purity :

  97.0

• Solubility :

  DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=CC=CN=C1N)N2C=NC=C2

• Molecular Formula :

  C9H8N4O

• Molecular Weight :

  188.19

• References & Citations :

  [1]Marinus T, et al. A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy[J]. Nucleic acids research, 2021, 49 (6) : e34-e34.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported