Phenylbiguanide (hydrochloride)
CAT:
804-HY-101331A
Size:
Inquire
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Phenylbiguanide (hydrochloride)
- CAS Number: 55-57-2
- UNSPSC Description: Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
- Target Antigen: 5-HT Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/phenylbiguanide-hydrochloride.html
- Purity: 99.80
- Solubility: 10 mM in DMSO
- Smiles: NC(NC(NC1=CC=CC=C1)=N)=N.Cl
- Molecular Weight: 213.67
- References & Citations: [1]Mair ID, et al. Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT3A(b)) expressed in Xenopus laevis oocytes. Br J Pharmacol. 1998 Aug;124(8):1667-74.|[2]Ataee R, et al. Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues. Arch Iran Med. 2010 Mar;13(2):120-5.|[3]de Vries A, et al. Characterisation of c-Fos expression in the central nervous system of mice following right atrialinjections of the 5-HT3 receptor agonist Phenylbiguanide. Auton Neurosci. 2005 Dec 30;123(1-2):62-75.
- Shipping Conditions: Room Temperature
- Storage Conditions: Store at room temperature 3 years
- Clinical Information: No Development Reported