Doxercalciferol

Doxercalciferol

• CAS Number: 54573-75-0
• UNSPSC Description: Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
• Target Antigen: VD/VDR
• Type: Reference compound
• Related Pathways: Vitamin D Related/Nuclear Receptor
• Applications: Cancer-programmed cell death
• Field of Research: Metabolic Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/Doxercalciferol.html
• Purity: 99.92
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](/C=C/[C@@H](C(C)C)C)C)CCC/2)[H])O)O
• Molecular Weight: 412.65
• References & Citations: [1]Noonan W, et al. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23(12):3824-30.|[2]Wang XX, et al. Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol. 2011 Mar;300(3):F801-10.|[3]Wang Y, et al. Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. J Am Soc Nephrol. 2012 Dec;23(12):1977-86.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: Launched