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IGF1 Receptor Antibody

CAT: 0796-AF7709-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0796-AF7709-01Size:50 µL
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Description
IGF1 Receptor Antibody (IGF1R Antibody) is a rabbit polyclonal antibody designed to detect endogenous levels of total Insulin-like Growth Factor 1 Receptor (IGF1R/CD221). IGF1R is a receptor tyrosine kinase involved in cell growth, survival, metabolism and signaling pathways associated with insulin-like growth factors. This antibody recognizes a C-terminal region of human IGF1R and is suitable for Western blot analysis in human, mouse and rat samples, making it useful for research in IGF1 signaling, cancer biology, cell proliferation and receptor tyrosine kinase pathways.
CAS Number
9007-83-4
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human IGF1 Receptor, corresponding to a region within C-terminal amino acids.
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Applications
WB
Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Dilution
WB 1:500-1:2000
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Specificity
IGF1 Receptor Antibody detects endogenous levels of total IGF1 Receptor.
FAQ
What is IGF1R? => IGF1R, also known as IGF1 Receptor or CD221, is a transmembrane receptor tyrosine kinase that mediates signaling triggered by insulin-like growth factors. What does this IGF1R antibody detect? => It detects endogenous levels of total IGF1 Receptor rather than a specific phosphorylated form. Can this antibody be used for Western blot? => Yes. It is validated for Western blot, with a recommended dilution range of 1:500–1:2000. Which species are reactive? => The antibody is reactive with human, mouse and rat samples.
Prediction Reactivity
Bovine, Rabbit, Dog, Chicken, Xenopus

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