Smad2 (Phospho Ser255) rabbit pAb

CAT:

855-ES20160-01

Size:

50 μL

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Synonyms: Mothers against decapentaplegic homolog 2 (MAD homolog 2;Mothers against DPP homolog 2;JV18-1;Mad-related protein 2;hMAD-2;SMAD family member 2;SMAD 2;Smad2;hSMAD2)
Gene ID: 4087
UniProt: Q15796
Cellular Locus: Cytoplasm. Nucleus. Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD4 complex, and exported out of the nucleus by interaction with RANBP1 (PubMed:16751101, PubMed:19289081). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity)..
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human Smad2 (Phospho Ser255)
Clonality: Polyclonal
Validated Applications: WB, ELISA, IHC
Stability: 1 year
Concentration: 1 mg/mL
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight: 55kD
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.