Nolatrexed

Nolatrexed

• CAS Number: 147149-76-6
• UNSPSC Description: Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils.
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/nolatrexed.html
• Smiles: O=C1N=C(NC2=CC=C(C)C(SC3=CC=NC=C3)=C12)N
• Molecular Weight: 284.34
• References & Citations: [1]Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days
• Shipping Conditions: Room temperature
• Clinical Information: Phase 3