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(S) -Sitagliptin (phosphate) (Standard)

CAT: 0804-HY-13749CRSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13749CRSize:1 Each
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Description
(S) -Sitagliptin (phosphate) (Standard) is the analytical standard of (S) -Sitagliptin (phosphate) . This product is intended for research and analytical applications. (S) -Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1].
CAS Number
823817-58-9
Product Name Alternative
(S) -MK-0431 (phosphate) (Standard)
UNSPSC
12352005
Target
Autophagy; Dipeptidyl Peptidase; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/s-sitagliptin-phosphate-standard.html
Smiles
O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O)(O)O
Molecular Formula
C16H18F6N5O5P
Molecular Weight
505.31
References & Citations
[1]Chi-Hung Ho, et al. Biocatalytic Continuous Manufacturing of Diabetes Drug: Plantwide Process Modeling, Optimization, and Environmental and Economic Analysis. ACS Sustainable Chem. Eng. 2019, 7, 1, 1038-1051.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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