β-D-Glucan

• Description :

  β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].

• UNSPSC :

  12352200

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Toll-like Receptor (TLR)

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/β-d-glucan.html

• Purity :

  99.00

• Solubility :

  1M NaOH : 50 mg/mL (ultrasonic; adjust pH to 12 with NaOH)

• Smiles :

  [beta-D-Glucan]

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Su Y, et al. pH-sensitive PEG-coated hyper-branched β-d-glucan derivative as carrier for CpG oligodeoxynucleotide delivery. Carbohydr Polym. 2020;246:116621. |[2]Gani A, et al. β-d-glucan as an enteric delivery vehicle for probiotics. Int J Biol Macromol. 2018;106:864-869. |[3]Jafaar ZM, et al. β-D-glucan inhibits endocrine-resistant breast cancer cell proliferation and alters gene expression. Int J Oncol. 2014;44 (4) :1365-1375.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [9041-22-9]