Products for Research Use Only
RegisterLogin

NoxA1ds

CAT: 0804-HY-P1435-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P1435-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NoxA1ds is a potent and highly selective NADPH oxidase 1 (NOX1) inhibitor (IC50=20 nM) . NoxA1ds inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. NoxA1ds attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. NoxA1ds can be used in the study of hypertension, atherosclerosis and tumors[1].
CAS Number
1435893-78-9
UNSPSC
12352209
Target
NADPH Oxidase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/noxa1ds.html
Purity
97.71
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
CC(C)[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H]1N(CCC1)C([C@@H](N)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C50H88N14O15
Molecular Weight
1125.32
References & Citations
[1]Ranayhossaini DJ, et al. Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration. J Biol Chem. 2013;288 (51) :36437-36450.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NOX1

Related Products

CatalogName
HY-RS28184Noxa1 Rat Pre-designed siRNA Set A
HY-RS09465NOXA1 Human Pre-designed siRNA Set A
HY-RS21666Noxa1 Mouse Pre-designed siRNA Set A

Alternative Products

CatalogName
BA8039-1NoxA1ds
T75949-01NoxA1ds TFA
TP1886L1-01NoxA1ds acetate (1435893-78-9 free base)

Popular Products