HIF-2α agonist 2
CAT:
804-HY-153016-05
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HIF-2α agonist 2
- CAS Number: 2750141-15-0
- UNSPSC Description: HIF-2α agonist 2 (compound 10) is a HIF-2α agonist with an EC50 value of 1.68 μM at the dose of 20 μM. HIF-2α agonist 2 is non-cytotoxic against 786-O-HRE-Luc cells. HIF-2α agonist 2 can be used for oxygen metabolism research[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/hif-2α-agonist-2.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=S1(N=C(C2=C1C=CC=C2)NC3=CC(Br)=CC(Br)=C3)=O
- Molecular Weight: 416.09
- References & Citations: [1]Yu Y, et al. Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation. Eur J Med Chem. 2021 Feb 5;211:112999.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported