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IA-Alkyne

CAT: 0804-HY-136205-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136205-01Size:5 mg
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Description
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection[1]. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling[2]. IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
930800-38-7
Product Name Alternative
Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
UNSPSC
12352211
Hazard Statement
H301, H311, H331, H341
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ia-alkyne.html
Concentration
10mM
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCCCC#C)CI
Molecular Formula
C8H12INO
Molecular Weight
265.09
Precautions
H301, H311, H331, H341
References & Citations
[1]David L. Use of trp channel agonists to treat infections. Patent US20130203715A1.|[2]Zorin NA, et al. Inhibition by iodoacetamide and acetylene of the H-D-exchange reaction catalyzed by Thiocapsa roseopersicina hydrogenase. Eur J Biochem. 1996 Oct 15;241 (2) :675-81.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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