Agaritine

• Description :

  Agaritine is a compound isolated from the commonly cultivated commercial mushroom Agaricus bisporus. Agaritine is hydrolyzed by an enzyme system present in the mushroom into 4- (hydroxymethyl) benzenediazonium ion, which is a carcinogen in mice. Agaritine is structurally similar to some known carcinogens and can be used for research in cancer and food safety[1][2].

• CAS Number :

  [2757-90-6]

• UNSPSC :

  12352005

• Target :

  HIV Protease

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/agaritine.html

• Smiles :

  OC([C@@H](N)CCC(NNC1=CC=C(CO)C=C1)=O)=O

• Molecular Formula :

  C12H17N3O4

• Molecular Weight :

  267.28

• References & Citations :

  [1]Ross A E, et al. Evidence for the occurrence and formation of diazonium ions in the Agaricus bisporus mushroom and its extracts[J]. Journal of agricultural and food chemistry, 1982, 30 (3) : 521-525.|[2]Ross A E, et al. Occurrence, stability and decomposition of beta-N [gamma-L (+) -glutamyl]-4-hydroxymethylphenylhydrazine (agaritine) from the mushroom Agaricus bisporus[J]. Food and Chemical Toxicology: an International Journal Published for the British Industrial Biological Research Association, 1982, 20 (6) : 903-907.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  Phase 1