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GAT107

CAT: 0804-HY-117611-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117611-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GAT107 (compound 1b) is a potent α7 nAChR ago-PAMs (positive allosteric modulators) [1].
CAS Number
1476807-74-5
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gat107.html
Smiles
O=S(C1=CC2=C(N[C@H](C3=CC=C(Br)C=C3)[C@@]4([H])[C@]2([H])C=CC4)C=C1)(N)=O
Molecular Formula
C18H17BrN2O2S
Molecular Weight
405.31
References & Citations
[1]Thakur GA, et al. Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4- (4-bromophenyl) -3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS) : an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors. J Med Chem. 2013 Nov 14;56 (21) :8943-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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