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W123

CAT: 0804-HY-116088Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116088Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
W123, a FTY720 analog, is a competitive sphingosine 1-phosphate type 1 (S1P1) receptor antagonist. W123 is measured by GTPγS activation, MAPK recruitment, cell migration, and ligand-induced receptor internalization[1].
CAS Number
1345982-24-2
Product Name Alternative
MK-0822
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/w123.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCNCC(NC1=CC=CC(CCCCCC)=C1)=O
Molecular Formula
C17H26N2O3
Molecular Weight
306.40
References & Citations
[1]Sindy H Wei, et al. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat Immunol. 2005 Dec;6 (12) :1228-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
C4064-1W123

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