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Zaltoprofen

CAT: 0804-HY-B0619-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0619-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Zaltoprofen (CN100), a non-steroidal anti-inflammatory drug (NSAID), is a preferential and orally active COX-2 inhibitor, with IC50s of 1.3 and 0.34 μM for COX-1 and COX-2, respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain[1][2][3].
CAS Number
74711-43-6
Product Name Alternative
CN100
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zaltoprofen.html
Purity
99.28
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C1=CC=C(SC2=C3C=CC=C2)C(CC3=O)=C1)C(O)=O
Molecular Formula
C17H14O3S
Molecular Weight
298.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Kawai S, et, al. Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells. Eur J Pharmacol. 1998 Apr 17;347 (1) :87-94.|[2]Hirate K, et, al. Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors. Neurosci Res. 2006 Apr;54 (4) :288-94.|[3]Kameyama T, et, al. Analgesic and antiinflammatory effects of 2- (10,11-dihydro-10-oxo-dibenzo[b, f]thiepin-2-yl) propionic acid in rat and mouse. Arzneimittelforschung. 1987 Jan;37 (1) :19-26.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
COX-1; COX-2

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CatalogName
MBS6063608-01Zaltoprofen

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