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Ku80/XRCC5 Rabbit Polyclonal Antibody

CAT: 0013-GTR17690872Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR17690872Size:100 µg
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Description
Ku80/XRCC5 Rabbit Polyclonal Antibody
Product Name Alternative
X-ray repair cross-complementing protein 5; 3.6.4.-; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) ; XRCC5; G22P2
UniProt
P13010
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Ku80.
Target
X-ray repair cross-complementing protein 5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purification
Immunogen affinity purified.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Dilution
Western blot, 0.1-0.5μg/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human Immunocytochemistry, 0.5-1μg/ml, Human, - Immunofluorescence, 2μg/ml, Human Immunocytochemistry/Immunofluorescence, 2μg/ml, Human Flow Cytometry (Fixed), 1-3μg/1x10^6 cells, Human
Form
Lyophilized
Molecular Weight
83 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IF, IHC, WB
Host or Source
Rabbit
Preservative
Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG

UniProtKB · P13010

DNA repair protein Ku80

XRCC5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13010
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
XRCC5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.99.18, 5.6.2.4
Processing
—
Secondary accessions
A8K3X5, Q0Z7V0, Q4VBQ5, Q53HH7, Q7M4N0, Q9UCQ0, Q9UCQ1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseIsomeraseLyase

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeNucleus

Biological process

DNA damageDNA recombinationDNA repairHost-virus interactionImmunityInnate immunityRibosome biogenesisTranscriptionTranscription regulation

Disease

Systemic lupus erythematosus

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