c-Fms-IN-8

c-Fms-IN-8

• CAS Number: 1255303-58-2
• UNSPSC Description: c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1].
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-fms-in-8.html
• Purity: 99.47
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: OCCOC1=CC=NC(C(N2CC(C3=CC=C(OCC4=CC=C(CC)C=C4)C(OC)=C3)C2)=O)=C1
• Molecular Weight: 462.54
• References & Citations: [1]Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported