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VU0486846

CAT: 0804-HY-121806-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121806-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VU0486846 is an orally active and selective muscarinic acetylcholine receptor M1 positive allosteric modulator (PAM) [1].
CAS Number
1788055-11-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu0486846.html
Purity
99.5
Smiles
O[C@@H](CCCC1)[C@H]1NC([C@@H](C2)OC3=CC=CC=C3N2CC4=CC=C(N5C=CC=N5)C=C4)=O
Molecular Formula
C25H28N4O3
Molecular Weight
432.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Bertron JL, et al. The discovery of VU0486846: steep SAR from a series of M1 PAMs based on a novel benzomorpholine core. Bioorg Med Chem Lett. 2018 Jul 1;28 (12) :2175-2179.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19263501-01VU0486846

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