H-Tyr-Tyr-OH

H-Tyr-Tyr-OH

• Product Name Alternative: NIK333
• CAS Number: 1050-28-8
• UNSPSC Description: H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme (ACE) with an IC50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure[1][2].
• Target Antigen: Angiotensin-converting Enzyme (ACE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/h-tyr-tyr-oh.html
• Purity: 97.0
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
• Smiles: OC1=CC=C(C[C@H](NC([C@@H](N)CC2=CC=C(C=C2)O)=O)C(O)=O)C=C1
• Molecular Weight: 344.367
• References & Citations: [1]Maher TJ, et al. Use of parenteral dipeptides to increase serum tyrosine levels and to enhance catecholamine-mediated neurotransmission. J Pharm Sci. 1990 Aug;79(8):685-7.|[2]Maruyama, et al. Purification and identification of angiotensin I-converting enzyme inhibitory peptides from Royal Jelly treated with protease. Nippon Shokuhin Kagaku Kogaku Kaishi. 2003.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported