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Vibsanin A

CAT: 0804-HY-N10393Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10393Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
72506-14-0
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease;TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vibsanin-a.html
Solubility
10 mM in DMSO
Smiles
C/C(C)=C\CC[C@@]1(/C=C/[C@H]([C@@]2(O[C@@H]2CC/C(CO)=C\C1)C)OC(/C=C(C)/C)=O)C
Molecular Weight
402.57
References & Citations
[1]Miura K, et, al. Identification of vibsanin A analog as a novel HSP90 inhibitor. Bioorg Med Chem. 2020 Jan 15;28(2):115253.|[2]Shen X, et, al. Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn. Biochem Biophys Res Commun. 2018 Jul 7;502(1):110-115.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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