Products for Research Use Only
RegisterLogin

ZSQ836

CAT: 0804-HY-164553Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-164553Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer[1].
CAS Number
2634811-35-9
UNSPSC
12352005
Target
Apoptosis; CDK
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zsq836.html
Smiles
ClC1=CN=C(N[C@H]2CN(CCC2)CC(NC3=CC=C([As]4SCCS4)C=C3)=O)N=C1C5=CNC6=CC=CC=C56
Molecular Formula
C27H28AsClN6OS2
Molecular Weight
627.06
References & Citations
[1]Cheng L, et al. Dual inhibition of CDK12/CDK13 targets both tumor and immune cells in ovarian cancer[J]. Cancer Research, 2022, 82 (19) : 3588-3602.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products