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Deltaflexin3

CAT: 0804-HY-163636-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163636-01Size:5 mg
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Description
Deltaflexin3 is a potent PDE6D inhibitor. Deltaflexin3 reduces the signaling of Ras and selectively decreases the KRAS mutant and PDE6D-dependent cancer cells growth[1].
CAS Number
2767277-64-3
Product Name Alternative
A-442b
UNSPSC
12352005
Target
Phosphodiesterase (PDE) ; Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/deltaflexin3.html
Smiles
O=C(N(CCCCCCC(N(CC)CC1=NC(NC)=NC=C1)=O)C(C)C)C2=CC=C(F)C=C2
Molecular Formula
C25H36FN5O2
Molecular Weight
457.58
References & Citations
[1]Kaya P, et al. An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth. J Med Chem. 2024 May 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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