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Disulergine

CAT: 0804-HY-119997Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119997Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Disulergine (CH 29-717) is an ergot alkaloid. Disulergine is a dopamine receptor agonist. Disulergine inhibits secretion of prolactin in rats. Disulergine inhibits growth hormone (GH) release[1][2][3].
CAS Number
59032-40-5
Product Name Alternative
CH 29-717
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/disulergine.html
Smiles
O=S(N[C@H](CN([C@@]1(CC2=CNC3=C2C4=CC=C3)[H])C)C[C@@]14[H])(N(C)C)=O
Molecular Formula
C17H24N4O2S
Molecular Weight
348.46
References & Citations
[1]Spada A, et al. Differential transduction of dopamine signal in different subtypes of human growth hormone-secreting adenomas. J Clin Endocrinol Metab. 1994 Feb;78 (2) :411-7.|[2]Markó M. Dopamine agonistic potency of two novel prolactin release-inhibiting ergolines. Eur J Pharmacol. 1984 Jun 1;101 (3-4) :263-6.|[3]Spada A, et al. In vitro effect of dopamine on growth hormone (GH) release from human GH-secreting pituitary adenomas. J Clin Endocrinol Metab. 1982 Oct;55 (4) :734-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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