Biocytin

Biocytin

• CAS Number: 576-19-2
• UNSPSC Description: Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ?-amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Biocytin.html
• Purity: 99.52
• Solubility: H2O : 50 mg/mL (ultrasonic)
• Smiles: N[C@@H](CCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)C(O)=O
• Molecular Weight: 372.48
• References & Citations: [1]Roth G, et al. Morphology and axonal projection pattern of neurons in the telencephalon of the fire-bellied toad Bombina orientalis: an anterograde, retrograde, and intracellular biocytin labeling study. J Comp Neurol. 2004 Oct 4;478(1):35-61.|[2]Mishra A, et al. Improved neuronal tract tracing with stable biocytin-derived neuroimaging agents. ACS Chem Neurosci. 2010 Feb 17;1(2):129-38.|[3]MacNeil MA, et al. Biocytin wide-field bipolar cells in rabbit retina selectively contact blue cones. J Comp Neurol. 2008 Jan 1;506(1):6-15.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported