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VAV3 antibody

CAT: 0710-FNab10378Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10378Size:100 µg
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Background
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms
Guanine nucleotide exchange factor VAV3 (VAV-3) |VAV3
Gene ID
10451
UniProt
Q9UKW4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Guanine nucleotide exchange factor VAV3
Target
VAV3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Stem Cells, Cell Division and Proliferation, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
90-100 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
2-39aa

UniProtKB · Q9UKW4

Guanine nucleotide exchange factor VAV3

VAV3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKW4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VAV3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VAV-3
EC number
—
Processing
—
Secondary accessions
B1AMM0, B1APV5, B4E232, B7ZLR1, E9PQ97, O60498, O95230, Q9Y5X8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Biological process

Angiogenesis

Molecular function

Guanine-nucleotide releasing factor

Ligand

Metal-bindingZinc

PTM

Phosphoprotein

Domain

RepeatSH2 domainSH3 domainZinc-finger

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