Atorvastatin lactone-d5

Atorvastatin lactone-d5

• UNSPSC Description: Atorvastatin lactone-d5 is a deuterated form of Atorvastatin lactone (HY-101873). Atorvastatin lactone is a proagent form of atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor[1].
• Target Antigen: HMG-CoA Reductase (HMGCR); Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Inflammation/Immunology
• Solubility: 10 mM in DMSO
• Smiles: [2H]C(C([2H])=C1[2H])=C(C([2H])=C1C2=C(N(CC[C@H]3OC(C[C@H](O)C3)=O)C(C(C)C)=C2C(NC4=CC=CC=C4)=O)C5=CC=C(F)C=C5)[2H]
• Molecular Weight: 545.66
• References & Citations: [1]Valesky RJ, et al. Automated enzyme inhibition assay method for the determination of atorvastatin-derived HMG-CoA reductase inhibitors in human plasma using radioactivity detection. J Pharmacol Toxicol Methods. 2008 Jan-Feb;57(1):61-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported